HIV anti-latency treatment mediated by macromolecular prodrugs of histone deacetylase inhibitor, panobinostat

Histone deacetylase inhibitors (HDACi) and panobinostat in particular are currently in the focus of intensive investigation as latency reversing agents against the human immunodeficiency virus (HIV). Regretfully, HDACi have dose limiting side-effects making controlled, optimized methods for delivery...

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Detalles Bibliográficos
Autores principales: Zuwala, Kaja, Smith, Anton A. A., Tolstrup, Martin, Zelikin, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003675/
https://www.ncbi.nlm.nih.gov/pubmed/29997778
http://dx.doi.org/10.1039/c5sc03257a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003675/
https://www.ncbi.nlm.nih.gov/pubmed/29997778
http://dx.doi.org/10.1039/c5sc03257a

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