Modulating D-amino acid oxidase (DAAO) substrate specificity through facilitated solvent access

D-amino acid oxidase (DAAO) degrades D-amino acids to produce α-ketoacids, hydrogen peroxide and ammonia. DAAO has often been investigated and engineered for industrial and clinical applications. We combined information from literature with a detailed analysis of the structure to engineer mammalian...

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Detalles Bibliográficos
Autores principales: Subramanian, Kalyanasundaram, Góra, Artur, Spruijt, Ruud, Mitusińska, Karolina, Suarez-Diez, Maria, Martins dos Santos, Vitor, Schaap, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003678/
https://www.ncbi.nlm.nih.gov/pubmed/29906280
http://dx.doi.org/10.1371/journal.pone.0198990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003678/
https://www.ncbi.nlm.nih.gov/pubmed/29906280
http://dx.doi.org/10.1371/journal.pone.0198990

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