Cargando…

Modulating D-amino acid oxidase (DAAO) substrate specificity through facilitated solvent access

D-amino acid oxidase (DAAO) degrades D-amino acids to produce α-ketoacids, hydrogen peroxide and ammonia. DAAO has often been investigated and engineered for industrial and clinical applications. We combined information from literature with a detailed analysis of the structure to engineer mammalian...

Descripción completa

Detalles Bibliográficos
Autores principales:	Subramanian, Kalyanasundaram, Góra, Artur, Spruijt, Ruud, Mitusińska, Karolina, Suarez-Diez, Maria, Martins dos Santos, Vitor, Schaap, Peter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003678/ https://www.ncbi.nlm.nih.gov/pubmed/29906280 http://dx.doi.org/10.1371/journal.pone.0198990

Ejemplares similares

The Therapeutic Potential of D-Amino Acid Oxidase (DAAO) Inhibitors
por: Smith, Sean M, et al.
Publicado: (2010)

Expression of D-Amino Acid Oxidase (DAO/DAAO) and D-Amino Acid Oxidase Activator (DAOA/G72) during Development and Aging in the Human Post-mortem Brain
por: Jagannath, Vinita, et al.
Publicado: (2017)

Study on a Single-Dose Toxicity Test of D-Amino Acid Oxidase (DAAO) Extracts Injected into the Tail Vein of Rats
por: Kang, Jungue, et al.
Publicado: (2013)

Simple Selection Procedure to Distinguish between Static and Flexible Loops
por: Mitusińska, Karolina, et al.
Publicado: (2020)

Distant Non-Obvious Mutations Influence the Activity of a Hyperthermophilic Pyrococcus furiosus Phosphoglucose Isomerase
por: Subramanian, Kalyanasundaram, et al.
Publicado: (2019)

Geometry-Based versus Small-Molecule Tracking Method for Tunnel Identification: Benefits and Pitfalls
por: Mitusińska, Karolina, et al.
Publicado: (2022)

Multipoint TvDAAO Mutants for Cephalosporin C Bioconversion
por: Atroshenko, Denis L., et al.
Publicado: (2019)

Mouse strain specificity of DAAO inhibitors‐mediated antinociception
por: Liu, Hao, et al.
Publicado: (2021)

Involvement of DAAO Overexpression in Delayed Hippocampal Neuronal Death
por: Liu, Hao, et al.
Publicado: (2022)

Exploring Solanum tuberosum Epoxide Hydrolase Internal Architecture by Water Molecules Tracking
por: Mitusińska, Karolina, et al.
Publicado: (2018)

Applications of water molecules for analysis of macromolecule properties
por: Mitusińska, Karolina, et al.
Publicado: (2020)

Deutsch-Amerikanische Akademie für Osteopathie (DAAO) E.V.
Publicado: (2020)

Structural and Evolutionary Analysis Indicate That the SARS-CoV-2 Mpro Is a Challenging Target for Small-Molecule Inhibitor Design
por: Bzówka, Maria, et al.
Publicado: (2020)

Computational Selectivity Assessment of Protease Inhibitors against SARS-CoV-2
por: Fischer, André, et al.
Publicado: (2021)

Structural Analysis of the Effect of Asn107Ser Mutation on Alg13 Activity and Alg13-Alg14 Complex Formation and Expanding the Phenotypic Variability of ALG13-CDG
por: Mitusińska, Karolina, et al.
Publicado: (2022)

AQUA-DUCT 1.0: structural and functional analysis of macromolecules from an intramolecular voids perspective
por: Magdziarz, Tomasz, et al.
Publicado: (2020)

Structure-function relationship between soluble epoxide hydrolases structure and their tunnel network
por: Mitusińska, Karolina, et al.
Publicado: (2021)

Evolution of tunnels in α/β-hydrolase fold proteins—What can we learn from studying epoxide hydrolases?
por: Bzówka, Maria, et al.
Publicado: (2022)

Mouse d-Amino-Acid Oxidase: Distribution and Physiological Substrates
por: Koga, Reiko, et al.
Publicado: (2017)

Cell Death Mechanisms Induced by CLytA-DAAO Chimeric Enzyme in Human Tumor Cell Lines
por: Fuentes-Baile, María, et al.
Publicado: (2020)

CLytA-DAAO, Free and Immobilized in Magnetic Nanoparticles, Induces Cell Death in Human Cancer Cells
por: Fuentes-Baile, María, et al.
Publicado: (2020)

CLytA-DAAO Chimeric Enzyme Bound to Magnetic Nanoparticles. A New Therapeutical Approach for Cancer Patients?
por: Fuentes-Baile, María, et al.
Publicado: (2021)

Identification of Crucial Amino Acids in Mouse Aldehyde Oxidase 3 That Determine Substrate Specificity
por: Mahro, Martin, et al.
Publicado: (2013)

Recombinant l‐Amino Acid Oxidase with Broad Substrate Spectrum for Co‐substrate Recycling in (S)‐Selective Transaminase‐Catalyzed Kinetic Resolutions
por: Heinks, Tobias, et al.
Publicado: (2022)

The substrate tolerance of alcohol oxidases
por: Pickl, Mathias, et al.
Publicado: (2015)

Performance of a zeolite modified with N,N-dimethyl dehydroabietylamine oxide (DAAO) for adsorption of humic acid assessed in batch and fixed bed columns
por: Liu, Shaogang, et al.
Publicado: (2018)

Molecular modeling studies of 1,2,4-triazine derivatives as novel h-DAAO inhibitors by 3D-QSAR, docking and dynamics simulations
por: Qian, Ping Ping, et al.
Publicado: (2018)

Comparative proteomics of Rhizopus delemar ATCC 20344 unravels the role of amino acid catabolism in fumarate accumulation
por: Odoni, Dorett I., et al.
Publicado: (2017)

Alteration in the plasma concentration of a DAAO inhibitor, 3-methylpyrazole-5-carboxylic acid, in the ketamine-treated rats and the influence on the pharmacokinetics of plasma d-tryptophan
por: HARUTA, Naomi, et al.
Publicado: (2011)

Formate as a supplementary substrate facilitates sugar metabolism and solvent production by Clostridium beijerinckii NCIMB 8052
por: Zhao, Ran, et al.
Publicado: (2023)

Expansion of the Substrate Specificity of Porcine Kidney D‐Amino Acid Oxidase for S‐Stereoselective Oxidation of 4‐Cl‐Benzhydrylamine
por: Yasukawa, Kazuyuki, et al.
Publicado: (2018)

Integration of heterogeneous molecular networks to unravel gene-regulation in Mycobacterium tuberculosis
por: van Dam, Jesse CJ, et al.
Publicado: (2014)

Modeling the Metabolic State of Mycobacterium tuberculosis Upon Infection
por: Rienksma, Rienk A., et al.
Publicado: (2018)

Modeling Host-Pathogen Interaction to Elucidate the Metabolic Drug Response of Intracellular Mycobacterium tuberculosis
por: Rienksma, Rienk A., et al.
Publicado: (2019)

Protein domain architectures provide a fast, efficient and scalable alternative to sequence-based methods for comparative functional genomics
por: Koehorst, Jasper J., et al.
Publicado: (2017)

Ancestral L-amino acid oxidases for deracemization and stereoinversion of amino acids
por: Nakano, Shogo, et al.
Publicado: (2020)

Influence of Solvent and Substrate on Hydrophobicity of PLA Films
por: Luque-Agudo, Verónica, et al.
Publicado: (2021)

Methods for the Detection of D-Amino-Acid Oxidase
por: Konno, Ryuichi
Publicado: (1998)

Assays of D-Amino Acid Oxidase Activity
por: Rosini, Elena, et al.
Publicado: (2018)

Structural Determinants of the Specific Activities of an L-Amino Acid Oxidase from Pseudoalteromonas luteoviolacea CPMOR-1 with Broad Substrate Specificity
por: Mamounis, Kyle J., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_glus6kbinuunsq57u9upbllvad