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How epigenome drives chromatin folding and dynamics, insights from efficient coarse-grained models of chromosomes
The 3D organization of chromosomes is crucial for regulating gene expression and cell function. Many experimental and polymer modeling efforts are dedicated to deciphering the mechanistic principles behind chromosome folding. Chromosomes are long and densely packed—topologically constrained—polymers...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003694/ https://www.ncbi.nlm.nih.gov/pubmed/29813054 http://dx.doi.org/10.1371/journal.pcbi.1006159 |