Thyroid transcription factor 1 enhances cellular statin sensitivity via perturbing cholesterol metabolism

We have discovered an unexpected connection between a critical lung development and cancer gene termed thyroid transcription factor 1 (TTF-1 also known as NKX2-1) and cholesterol metabolism. Our published work implicates that TTF-1 positively regulates miR-33a which is known to repress ATP-binding c...

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Detalles Bibliográficos
Autores principales: Lai, Shao-Chiang, Phelps, Cody A., Short, Aleena M., Dutta, Sucharita M., Mu, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003839/
https://www.ncbi.nlm.nih.gov/pubmed/29551766
http://dx.doi.org/10.1038/s41388-018-0174-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003839/
https://www.ncbi.nlm.nih.gov/pubmed/29551766
http://dx.doi.org/10.1038/s41388-018-0174-7

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