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Thyroid transcription factor 1 enhances cellular statin sensitivity via perturbing cholesterol metabolism
We have discovered an unexpected connection between a critical lung development and cancer gene termed thyroid transcription factor 1 (TTF-1 also known as NKX2-1) and cholesterol metabolism. Our published work implicates that TTF-1 positively regulates miR-33a which is known to repress ATP-binding c...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003839/ https://www.ncbi.nlm.nih.gov/pubmed/29551766 http://dx.doi.org/10.1038/s41388-018-0174-7 |