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The value of (99m)Tc-MAA SPECT/CT for lung shunt estimation in (90)Y radioembolization: a phantom and patient study

BACKGROUND: A major toxicity concern in radioembolization therapy of hepatic malignancies is radiation-induced pneumonitis and sclerosis due to hepatopulmonary shunting of (90)Y microspheres. Currently, (99m)Tc macroaggregated albumin ((99m)Tc-MAA) imaging is used to estimate the lung shunt fraction...

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Detalles Bibliográficos
Autores principales: Allred, Jonathan D., Niedbala, Jeremy, Mikell, Justin K., Owen, Dawn, Frey, Kirk A., Dewaraja, Yuni K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003896/
https://www.ncbi.nlm.nih.gov/pubmed/29904808
http://dx.doi.org/10.1186/s13550-018-0402-8