Comparison of Two Protocols of Carbon Tetrachloride-Induced Cirrhosis in Rats – Improving Yield and Reproducibility

Despite being a cardinal experimental model, the induction of cirrhosis in rats by repeated exposure to carbon tetrachloride (CCl4) has low reproducibility. Here, we compared two models of cirrhosis induced by orogastric administration of CCl4 once (CCl4-1xWk) or twice a week (CCl4-2xWk) for 12 week...

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Detalles Bibliográficos
Autores principales: Fortea, José I, Fernández-Mena, Carolina, Puerto, Marta, Ripoll, Cristina, Almagro, Jorge, Bañares, Juan, Bellón, José M., Bañares, Rafael, Vaquero, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003930/
https://www.ncbi.nlm.nih.gov/pubmed/29907790
http://dx.doi.org/10.1038/s41598-018-27427-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003930/
https://www.ncbi.nlm.nih.gov/pubmed/29907790
http://dx.doi.org/10.1038/s41598-018-27427-9

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