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Substance P modulates bone remodeling properties of murine osteoblasts and osteoclasts

Clinical observations suggest neuronal control of bone remodeling. Sensory nerve fibers innervating bone, bone marrow and periosteum signal via neurotransmitters including substance P (SP). In previous studies we observed impaired biomechanical and structural bone parameters in tachykinin (Tac) 1-de...

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Detalles Bibliográficos
Autores principales: Niedermair, Tanja, Schirner, Stephan, Seebröker, Raphael, Straub, Rainer H., Grässel, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003941/
https://www.ncbi.nlm.nih.gov/pubmed/29907830
http://dx.doi.org/10.1038/s41598-018-27432-y