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Transmission-clearance trade-offs indicate that dengue virulence evolution depends on epidemiological context
An extensive body of theory addresses the topic of pathogen virulence evolution, yet few studies have empirically demonstrated the presence of fitness trade-offs that would select for intermediate virulence. Here we show the presence of transmission-clearance trade-offs in dengue virus using viremia...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003961/ https://www.ncbi.nlm.nih.gov/pubmed/29907741 http://dx.doi.org/10.1038/s41467-018-04595-w |