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Transmission-clearance trade-offs indicate that dengue virulence evolution depends on epidemiological context

An extensive body of theory addresses the topic of pathogen virulence evolution, yet few studies have empirically demonstrated the presence of fitness trade-offs that would select for intermediate virulence. Here we show the presence of transmission-clearance trade-offs in dengue virus using viremia...

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Detalles Bibliográficos
Autores principales: Ben-Shachar, Rotem, Koelle, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003961/
https://www.ncbi.nlm.nih.gov/pubmed/29907741
http://dx.doi.org/10.1038/s41467-018-04595-w