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VRK1 and AURKB form a complex that cross inhibit their kinase activity and the phosphorylation of histone H3 in the progression of mitosis

Regulation of cell division requires the integration of signals implicated in chromatin reorganization and coordination of its sequential changes in mitosis. Vaccinia-related kinase 1 (VRK1) and Aurora B (AURKB) are two nuclear kinases involved in different steps of cell division. We have studied wh...

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Detalles Bibliográficos
Autores principales: Moura, David S., Campillo-Marcos, Ignacio, Vázquez-Cedeira, Marta, Lazo, Pedro A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003988/
https://www.ncbi.nlm.nih.gov/pubmed/29340707
http://dx.doi.org/10.1007/s00018-018-2746-7