TSC1 and TSC2 regulate cilia length and canonical Hedgehog signaling via different mechanisms

Primary cilia are sensory organelles that coordinate multiple cellular signaling pathways, including Hedgehog (HH), Wingless/Int (WNT) and Transforming Growth Factor-β (TGF-β) signaling. Similarly, primary cilia have been implicated in regulation of mTOR signaling, in which Tuberous Sclerosis Comple...

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Detalles Bibliográficos
Autores principales: Rosengren, Thomas, Larsen, Lasse Jonsgaard, Pedersen, Lotte Bang, Christensen, Søren Tvorup, Møller, Lisbeth Birk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003990/
https://www.ncbi.nlm.nih.gov/pubmed/29396625
http://dx.doi.org/10.1007/s00018-018-2761-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003990/
https://www.ncbi.nlm.nih.gov/pubmed/29396625
http://dx.doi.org/10.1007/s00018-018-2761-8

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