Cargando…
TSC1 and TSC2 regulate cilia length and canonical Hedgehog signaling via different mechanisms
Primary cilia are sensory organelles that coordinate multiple cellular signaling pathways, including Hedgehog (HH), Wingless/Int (WNT) and Transforming Growth Factor-β (TGF-β) signaling. Similarly, primary cilia have been implicated in regulation of mTOR signaling, in which Tuberous Sclerosis Comple...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003990/ https://www.ncbi.nlm.nih.gov/pubmed/29396625 http://dx.doi.org/10.1007/s00018-018-2761-8 |