Comprehensive Proteoform Characterization of Plasma Complement Component C8αβγ by Hybrid Mass Spectrometry Approaches

The human complement hetero-trimeric C8αβγ (C8) protein assembly (~ 150 kDa) is an important component of the membrane attack complex (MAC). C8 initiates membrane penetration and coordinates MAC pore formation. Here, we charted in detail the structural micro-heterogeneity within C8, purified from hu...

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Detalles Bibliográficos
Autores principales: Franc, Vojtech, Zhu, Jing, Heck, Albert J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Focus: Mass Spectrometry in Glycobiology and Related Fields: Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003997/
https://www.ncbi.nlm.nih.gov/pubmed/29532326
http://dx.doi.org/10.1007/s13361-018-1901-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003997/
https://www.ncbi.nlm.nih.gov/pubmed/29532326
http://dx.doi.org/10.1007/s13361-018-1901-6

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