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Efficient RNA drug delivery using red blood cell extracellular vesicles

Most of the current methods for programmable RNA drug therapies are unsuitable for the clinic due to low uptake efficiency and high cytotoxicity. Extracellular vesicles (EVs) could solve these problems because they represent a natural mode of intercellular communication. However, current cellular so...

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Detalles Bibliográficos
Autores principales: Usman, Waqas Muhammad, Pham, Tin Chanh, Kwok, Yuk Yan, Vu, Luyen Tien, Ma, Victor, Peng, Boya, Chan, Yuen San, Wei, Likun, Chin, Siew Mei, Azad, Ajijur, He, Alex Bai-Liang, Leung, Anskar Y. H., Yang, Mengsu, Shyh-Chang, Ng, Cho, William C., Shi, Jiahai, Le, Minh T. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004015/
https://www.ncbi.nlm.nih.gov/pubmed/29907766
http://dx.doi.org/10.1038/s41467-018-04791-8