SRSF3 recruits DROSHA to the basal junction of primary microRNAs

The Microprocessor complex, consisting of an RNase III DROSHA and the DGCR8 dimer, cleaves primary microRNA transcripts (pri-miRNAs) to initiate microRNA (miRNA) maturation. Pri-miRNAs are stem–loop RNAs, and ∼79% of them contain at least one of the three major and conserved RNA motifs, UG, UGU, and...

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Detalles Bibliográficos
Autores principales: Kim, Kijun, Nguyen, Trung Duc, Li, Shaohua, Nguyen, Tuan Anh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004053/
https://www.ncbi.nlm.nih.gov/pubmed/29615481
http://dx.doi.org/10.1261/rna.065862.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004053/
https://www.ncbi.nlm.nih.gov/pubmed/29615481
http://dx.doi.org/10.1261/rna.065862.118

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