Role of the novel endoribonuclease SLFN14 and its disease-causing mutations in ribosomal degradation

Platelets are anucleate and mostly ribosome-free cells within the bloodstream, derived from megakaryocytes within bone marrow and crucial for cessation of bleeding at sites of injury. Inherited thrombocytopenias are a group of disorders characterized by a low platelet count and are frequently associ...

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Detalles Bibliográficos
Autores principales: Fletcher, Sarah J., Pisareva, Vera P., Khan, Abdullah O., Tcherepanov, Andrew, Morgan, Neil V., Pisarev, Andrey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004054/
https://www.ncbi.nlm.nih.gov/pubmed/29678925
http://dx.doi.org/10.1261/rna.066415.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004054/
https://www.ncbi.nlm.nih.gov/pubmed/29678925
http://dx.doi.org/10.1261/rna.066415.118

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