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The surveillance of pre-mRNA splicing is an early step in C. elegans RNAi of endogenous genes

RNAi pathways detect and silence foreign nucleic acids such as viruses as well as endogenous genes in many species. The phylogenetic profile across eukaryotes of proteins that mediate key steps in RNAi is correlated with the profiles of multiple mRNA splicing proteins and with intron number, suggest...

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Detalles Bibliográficos
Autores principales: Newman, Martin A., Ji, Fei, Fischer, Sylvia E.J., Anselmo, Anthony, Sadreyev, Ruslan I., Ruvkun, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004069/
https://www.ncbi.nlm.nih.gov/pubmed/29739806
http://dx.doi.org/10.1101/gad.311514.118