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The surveillance of pre-mRNA splicing is an early step in C. elegans RNAi of endogenous genes
RNAi pathways detect and silence foreign nucleic acids such as viruses as well as endogenous genes in many species. The phylogenetic profile across eukaryotes of proteins that mediate key steps in RNAi is correlated with the profiles of multiple mRNA splicing proteins and with intron number, suggest...
Autores principales: | Newman, Martin A., Ji, Fei, Fischer, Sylvia E.J., Anselmo, Anthony, Sadreyev, Ruslan I., Ruvkun, Gary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004069/ https://www.ncbi.nlm.nih.gov/pubmed/29739806 http://dx.doi.org/10.1101/gad.311514.118 |
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