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Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells

Cholesterol is a major constituent of myelin membranes, which insulate axons and allow saltatory conduction. Therefore, Schwann cells, the myelinating glia of the peripheral nervous system, need to produce large amounts of cholesterol. Here, we define a crucial role of the transcription factor Maf i...

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Detalles Bibliográficos
Autores principales: Kim, Minchul, Wende, Hagen, Walcher, Jan, Kühnemund, Johannes, Cheret, Cyril, Kempa, Stefan, McShane, Erik, Selbach, Matthias, Lewin, Gary R., Birchmeier, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004071/
https://www.ncbi.nlm.nih.gov/pubmed/29748249
http://dx.doi.org/10.1101/gad.310490.117