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The mTOR-S6 kinase pathway promotes stress granule assembly

Stress granules are cytoplasmic mRNA-protein complexes that form upon the inhibition of translation initiation and promote cell survival in response to environmental insults. However, they are often associated with pathologies, including neurodegeneration and cancer, and changes in their dynamics ar...

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Detalles Bibliográficos
Autores principales: Sfakianos, Aristeidis P., Mellor, Laura E., Pang, Yoke Fei, Kritsiligkou, Paraskevi, Needs, Hope, Abou-Hamdan, Hussein, Désaubry, Laurent, Poulin, Gino B., Ashe, Mark P., Whitmarsh, Alan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004310/
https://www.ncbi.nlm.nih.gov/pubmed/29523872
http://dx.doi.org/10.1038/s41418-018-0076-9