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The mTOR-S6 kinase pathway promotes stress granule assembly
Stress granules are cytoplasmic mRNA-protein complexes that form upon the inhibition of translation initiation and promote cell survival in response to environmental insults. However, they are often associated with pathologies, including neurodegeneration and cancer, and changes in their dynamics ar...
Autores principales: | Sfakianos, Aristeidis P., Mellor, Laura E., Pang, Yoke Fei, Kritsiligkou, Paraskevi, Needs, Hope, Abou-Hamdan, Hussein, Désaubry, Laurent, Poulin, Gino B., Ashe, Mark P., Whitmarsh, Alan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004310/ https://www.ncbi.nlm.nih.gov/pubmed/29523872 http://dx.doi.org/10.1038/s41418-018-0076-9 |
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