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Pharmacokinetics of Human Red Blood Cell Microparticles Prepared Using High-Pressure Extrusion Method

Red blood cell microparticles (RMPs) is a high potency hemostatic agent, which may serve as a viable therapeutic approach. They generate thrombin in vitro and effective in arresting bleeding in animal bleeding models. However, prior to ascertaining the clinical efficacy of RMPs, detailed preclinical...

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Detalles Bibliográficos
Autores principales: Jy, Wenche, Rehni, Ashish K., Bidot, Carlos, Navarro-Quero, Hever, Haase, Conner R., Koch, Sebastian, Ahn, Yeon S., Dave, Kunjan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004370/
https://www.ncbi.nlm.nih.gov/pubmed/29942257
http://dx.doi.org/10.3389/fphar.2018.00599