Elevated Nicotinamide Phosphoribosyl Transferase in Skeletal Muscle Augments Exercise Performance and Mitochondrial Respiratory Capacity Following Exercise Training

Mice overexpressing NAMPT in skeletal muscle (NamptTg mice) develop higher exercise endurance and maximal aerobic capacity (VO(2)max) following voluntary exercise training compared to wild-type (WT) mice. Here, we aimed to investigate the mechanisms underlying by determining skeletal muscle mitochon...

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Detalles Bibliográficos
Autores principales: Brouwers, Bram, Stephens, Natalie A., Costford, Sheila R., Hopf, Meghan E., Ayala, Julio E., Yi, Fanchao, Xie, Hui, Li, Jian-Liang, Gardell, Stephen J., Sparks, Lauren M., Smith, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004371/
https://www.ncbi.nlm.nih.gov/pubmed/29942262
http://dx.doi.org/10.3389/fphys.2018.00704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004371/
https://www.ncbi.nlm.nih.gov/pubmed/29942262
http://dx.doi.org/10.3389/fphys.2018.00704

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