Augmented Fibroblast Growth Factor-23 Secretion in Bone Locally Contributes to Impaired Bone Mineralization in Chronic Kidney Disease in Mice

Chronic kidney disease-mineral and bone disorder (CKD-MBD) is a systemic disorder of mineral and bone metabolism caused by CKD. Impaired bone mineralization together with increased bony secretion of fibroblast growth factor-23 (FGF23) are hallmarks of CKD-MBD. We recently showed that FGF23 suppresse...

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Detalles Bibliográficos
Autores principales: Andrukhova, Olena, Schüler, Christiane, Bergow, Claudia, Petric, Alexandra, Erben, Reinhold G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004378/
https://www.ncbi.nlm.nih.gov/pubmed/29942284
http://dx.doi.org/10.3389/fendo.2018.00311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004378/
https://www.ncbi.nlm.nih.gov/pubmed/29942284
http://dx.doi.org/10.3389/fendo.2018.00311

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