Ectonucleotidase-Mediated Suppression of Lupus Autoimmunity and Vascular Dysfunction

OBJECTIVES: CD39 and CD73 are surface enzymes that jut into the extracellular space where they mediate the step-wise phosphohydrolysis of the autocrine and paracrine danger signals ATP and ADP into anti-inflammatory adenosine. Given the role of vascular and immune cells’ “purinergic halo” in maintai...

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Detalles Bibliográficos
Autores principales: Knight, Jason S., Mazza, Levi F., Yalavarthi, Srilakshmi, Sule, Gautam, Ali, Ramadan A., Hodgin, Jeffrey B., Kanthi, Yogendra, Pinsky, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004379/
https://www.ncbi.nlm.nih.gov/pubmed/29942314
http://dx.doi.org/10.3389/fimmu.2018.01322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004379/
https://www.ncbi.nlm.nih.gov/pubmed/29942314
http://dx.doi.org/10.3389/fimmu.2018.01322

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