Extending in Silico Protein Target Prediction Models to Include Functional Effects

In silico protein target deconvolution is frequently used for mechanism-of-action investigations; however existing protocols usually do not predict compound functional effects, such as activation or inhibition, upon binding to their protein counterparts. This study is hence concerned with including...

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Detalles Bibliográficos
Autores principales: Mervin, Lewis H., Afzal, Avid M., Brive, Lars, Engkvist, Ola, Bender, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004408/
https://www.ncbi.nlm.nih.gov/pubmed/29942259
http://dx.doi.org/10.3389/fphar.2018.00613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004408/
https://www.ncbi.nlm.nih.gov/pubmed/29942259
http://dx.doi.org/10.3389/fphar.2018.00613

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