Cosmosiin Increases ADAM10 Expression via Mechanisms Involving 5’UTR and PI3K Signaling

The α-secretase “a disintegrin and metalloproteinase domain-containing protein” (ADAM10) is involved in the processing of amyloid precursor protein (APP). Upregulation of ADAM10 precludes the generation of neurotoxic β-amyloid protein (Aβ) and represents a plausible therapeutic strategy for Alzheime...

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Detalles Bibliográficos
Autores principales: Min, Zhuo, Tang, Ying, Hu, Xiao-Tong, Zhu, Bing-Lin, Ma, Yuan-Lin, Zha, Jing-Si, Deng, Xiao-Juan, Yan, Zhen, Chen, Guo-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004422/
https://www.ncbi.nlm.nih.gov/pubmed/29942252
http://dx.doi.org/10.3389/fnmol.2018.00198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004422/
https://www.ncbi.nlm.nih.gov/pubmed/29942252
http://dx.doi.org/10.3389/fnmol.2018.00198

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