The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells

Cancer cells are reprogrammed to consume large amounts of glucose to support anabolic biosynthetic pathways. However, blood perfusion and consequently the supply with glucose are frequently inadequate in solid cancers. PEPCK-M (PCK2), the mitochondrial isoform of phosphoenolpyruvate carboxykinase (P...

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Detalles Bibliográficos
Autores principales: Leithner, Katharina, Triebl, Alexander, Trötzmüller, Martin, Hinteregger, Barbara, Leko, Petra, Wieser, Beatrix I., Grasmann, Gabriele, Bertsch, Alexandra L., Züllig, Thomas, Stacher, Elvira, Valli, Alessandro, Prassl, Ruth, Olschewski, Andrea, Harris, Adrian L., Köfeler, Harald C., Olschewski, Horst, Hrzenjak, Andelko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004450/
https://www.ncbi.nlm.nih.gov/pubmed/29844165
http://dx.doi.org/10.1073/pnas.1719871115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004450/
https://www.ncbi.nlm.nih.gov/pubmed/29844165
http://dx.doi.org/10.1073/pnas.1719871115

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