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Activated integrins identify functional antigen-specific CD8(+) T cells within minutes after antigen stimulation
Immediate β(2)-integrin activation upon T cell receptor stimulation is critical for effective interaction between T cells and their targets and may therefore be used for the rapid identification and isolation of functional T cells. We present a simple and sensitive flow cytometry-based assay to asse...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004473/ https://www.ncbi.nlm.nih.gov/pubmed/29844168 http://dx.doi.org/10.1073/pnas.1720714115 |