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Activated integrins identify functional antigen-specific CD8(+) T cells within minutes after antigen stimulation

Immediate β(2)-integrin activation upon T cell receptor stimulation is critical for effective interaction between T cells and their targets and may therefore be used for the rapid identification and isolation of functional T cells. We present a simple and sensitive flow cytometry-based assay to asse...

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Detalles Bibliográficos
Autores principales:	Dimitrov, Stoyan, Gouttefangeas, Cécile, Besedovsky, Luciana, Jensen, Anja T. R., Chandran, P. Anoop, Rusch, Elisa, Businger, Ramona, Schindler, Michael, Lange, Tanja, Born, Jan, Rammensee, Hans-Georg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2018
Materias:	PNAS Plus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004473/ https://www.ncbi.nlm.nih.gov/pubmed/29844168 http://dx.doi.org/10.1073/pnas.1720714115

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