Structural basis for MTR4–ZCCHC8 interactions that stimulate the MTR4 helicase in the nuclear exosome-targeting complex

The nuclear exosome-targeting (NEXT) complex functions as an RNA exosome cofactor and is involved in surveillance and turnover of aberrant transcripts and noncoding RNAs. NEXT is a ternary complex composed of the RNA-binding protein RBM7, the scaffold zinc-knuckle protein ZCCHC8, and the helicase MT...

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Detalles Bibliográficos
Autores principales: Puno, M. Rhyan, Lima, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004480/
https://www.ncbi.nlm.nih.gov/pubmed/29844170
http://dx.doi.org/10.1073/pnas.1803530115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004480/
https://www.ncbi.nlm.nih.gov/pubmed/29844170
http://dx.doi.org/10.1073/pnas.1803530115

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