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Increase in chemokine CXCL1 by ERβ ligand treatment is a key mediator in promoting axon myelination

Estrogen receptor β (ERβ) ligands promote remyelination in mouse models of multiple sclerosis. Recent work using experimental autoimmune encephalomyelitis (EAE) has shown that ERβ ligands induce axon remyelination, but impact peripheral inflammation to varying degrees. To identify if ERβ ligands ini...

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Detalles Bibliográficos
Autores principales: Karim, Hawra, Kim, Sung Hoon, Lapato, Andrew S., Yasui, Norio, Katzenellenbogen, John A., Tiwari-Woodruff, Seema K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004485/
https://www.ncbi.nlm.nih.gov/pubmed/29844175
http://dx.doi.org/10.1073/pnas.1721732115