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Expansion of cat-ELCCA for the Discovery of Small Molecule Inhibitors of the Pre-let-7–Lin28 RNA–Protein Interaction

[Image: see text] Dysregulation of microRNA (miRNA) expression has been linked to many human diseases; however, because of the challenges associated with RNA-targeted drug discovery, additional approaches are needed for probing miRNA biology. The emerging regulatory role of miRNA-binding proteins in...

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Detalles Bibliográficos
Autores principales: Lorenz, Daniel A., Kaur, Tanpreet, Kerk, Samuel A., Gallagher, Erin E., Sandoval, Jorge, Garner, Amanda L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004563/
https://www.ncbi.nlm.nih.gov/pubmed/29937975
http://dx.doi.org/10.1021/acsmedchemlett.8b00126