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Renitence vacuoles facilitate protection against phagolysosomal damage in activated macrophages

As professional phagocytes, macrophages are susceptible to endolysosomal membrane damage inflicted by the pathogens and noxious particles they ingest. Whether macrophages have mechanisms for limiting such damage is not well understood. Previously, we reported a phenomenon, termed “inducible renitenc...

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Detalles Bibliográficos
Autores principales: Wong, Amanda O., Marthi, Matangi, Mendel, Zachary I., Gregorka, Brian, Swanson, Michele S., Swanson, Joel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004576/
https://www.ncbi.nlm.nih.gov/pubmed/29282279
http://dx.doi.org/10.1091/mbc.E17-07-0486