Cargando…

Fibronectin type III and intracellular domains of Toll-like receptor 4 interactor with leucine-rich repeats (Tril) are required for developmental signaling

Toll-like receptor 4 interactor with leucine-rich repeats (Tril) functions as a coreceptor for Toll-like receptors (Tlrs) to mediate innate immune responses in adults. In embryos, Tril signals to promote degradation of the Bmp inhibitor, Smad7, to allow for blood formation. It is not known whether t...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Hyung-Seok, McKnite, Autumn, Xie, Yuanyuan, Christian, Jan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004582/
https://www.ncbi.nlm.nih.gov/pubmed/29298840
http://dx.doi.org/10.1091/mbc.E17-07-0446