Ventricular pro-arrhythmic phenotype, arrhythmic substrate, ageing and mitochondrial dysfunction in peroxisome proliferator activated receptor-γ coactivator-1β deficient (Pgc-1β(−/−)) murine hearts

INTRODUCTION: Ageing and age-related bioenergetic conditions including obesity, diabetes mellitus and heart failure constitute clinical ventricular arrhythmic risk factors. MATERIALS AND METHODS: Pro-arrhythmic properties in electrocardiographic and intracellular recordings were compared in young an...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahmad, Shiraz, Valli, Haseeb, Chadda, Karan R., Cranley, James, Jeevaratnam, Kamalan, Huang, Christopher L.-H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ireland 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004599/
https://www.ncbi.nlm.nih.gov/pubmed/29763629
http://dx.doi.org/10.1016/j.mad.2018.05.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004599/
https://www.ncbi.nlm.nih.gov/pubmed/29763629
http://dx.doi.org/10.1016/j.mad.2018.05.004

Ejemplares similares