Quantification and pharmacokinetic study of tumor-targeting agent MHI148-clorgyline amide in mouse plasma using liquid chromatography-electrospray ionization tandem mass spectrometry

A high-performance liquid chromatography-electrospray ionization tandem mass spectrometric (HPLC-ESI-MS/MS) method was developed for the quantification of MHI148-clorgyline amide (NMI-amide), a novel tumor-targeting monoamine oxidase A inhibitor, in mouse plasma. The method was validated in terms of...

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Detalles Bibliográficos
Autores principales: Wang, Zhijun, Olenyuk, Bogdan Z., Shih, Jean Chen, Wang, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004616/
https://www.ncbi.nlm.nih.gov/pubmed/29922483
http://dx.doi.org/10.1016/j.jpha.2017.10.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004616/
https://www.ncbi.nlm.nih.gov/pubmed/29922483
http://dx.doi.org/10.1016/j.jpha.2017.10.001

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