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Simultaneous determination of acetaminophen and oxycodone in human plasma by LC–MS/MS and its application to a pharmacokinetic study

A simple and rapid liquid chromatography–tandem mass spectrometry (LC–MS/MS) method was developed and validated for simultaneous determination of acetaminophen and oxycodone in human plasma. Acetaminophen-d4 and oxycodone-d3 were used as internal standards. The challenge encountered in the method de...

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Detalles Bibliográficos
Autores principales:	Lu, Wei, Zhao, Shunbo, Gong, Meng, Sun, Luning, Ding, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Xi'an Jiaotong University 2018
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004620/ https://www.ncbi.nlm.nih.gov/pubmed/29922484 http://dx.doi.org/10.1016/j.jpha.2018.01.006

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