Sesquiterpene lactone 6-O-angeloylplenolin reverses vincristine resistance by inhibiting YB-1 nuclear translocation in colon carcinoma cells

Multidrug resistance (MDR) is a major obstacle to cancer chemotherapy efficacy. In the present study, 6-O-angeloylplenolin repressed the overexpression of ATP binding cassette subfamily B member 1 (MDR1) and increasing the intracellular concentration of anticancer drugs. A reduction in P-glycoprotei...

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Detalles Bibliográficos
Autores principales: Li, Changlong, Wu, Hezhen, Yang, Yanfang, Liu, Jianwen, Chen, Zhenwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004700/
https://www.ncbi.nlm.nih.gov/pubmed/29928343
http://dx.doi.org/10.3892/ol.2018.8592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004700/
https://www.ncbi.nlm.nih.gov/pubmed/29928343
http://dx.doi.org/10.3892/ol.2018.8592

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