A Fresh Look at Huntingtin mRNA Processing in Huntington’s Disease

Huntington’s disease (HD) is an inherited neurodegenerative disorder caused by a mutation that expands the polyglutamine (CAG) repeat in exon 1 of the huntingtin (HTT) gene. Wild-type HTT protein interacts with other proteins to protect cells against toxic stimuli, mediate vesicle transport and endo...

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Detalles Bibliográficos
Autores principales: Romo, Lindsay, Mohn, Emily S., Aronin, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004895/
https://www.ncbi.nlm.nih.gov/pubmed/29865084
http://dx.doi.org/10.3233/JHD-180292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004895/
https://www.ncbi.nlm.nih.gov/pubmed/29865084
http://dx.doi.org/10.3233/JHD-180292

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