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Best Practices for Generating and Using Alpha-Synuclein Pre-Formed Fibrils to Model Parkinson’s Disease in Rodents

Parkinson’s disease (PD) is the second most common neurodegenerative disease, affecting approximately one-percent of the population over the age of sixty. Although many animal models have been developed to study this disease, each model presents its own advantages and caveats. A unique model has ari...

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Detalles Bibliográficos
Autores principales: Polinski, Nicole K., Volpicelli-Daley, Laura A., Sortwell, Caryl E., Luk, Kelvin C., Cremades, Nunilo, Gottler, Lindsey M., Froula, Jessica, Duffy, Megan F., Lee, Virginia M.Y., Martinez, Terina N., Dave, Kuldip D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004926/
https://www.ncbi.nlm.nih.gov/pubmed/29400668
http://dx.doi.org/10.3233/JPD-171248