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Temporal Gene Expression and DNA Methylation during Embryonic Stem Cell Derivation

OBJECTIVE: Dual inhibition of mitogen-activated protein kinase (MAPK) kinase (also known as MEK) and transforming growth factor β (TGFβ) type I receptors by PD0325901 and SB431542, known as R2i has been introduced as a highly efficient approach to the generation of mouse embryonic stem cells (ESC)....

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Detalles Bibliográficos
Autores principales: Samadian, Azam, Hesaraki, Mahdi, Mollamohammadi, Sepideh, Asgari, Behrouz, Totonchi, Mehdi, Baharvand, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004995/
https://www.ncbi.nlm.nih.gov/pubmed/29845790
http://dx.doi.org/10.22074/cellj.2018.5482