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Temporal Gene Expression and DNA Methylation during Embryonic Stem Cell Derivation
OBJECTIVE: Dual inhibition of mitogen-activated protein kinase (MAPK) kinase (also known as MEK) and transforming growth factor β (TGFβ) type I receptors by PD0325901 and SB431542, known as R2i has been introduced as a highly efficient approach to the generation of mouse embryonic stem cells (ESC)....
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royan Institute
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004995/ https://www.ncbi.nlm.nih.gov/pubmed/29845790 http://dx.doi.org/10.22074/cellj.2018.5482 |