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Construction of homogeneous antibody–drug conjugates using site-selective protein chemistry

Systemic chemotherapy, the current standard of care for the treatment of cancer, is rarely curative and is often accompanied by debilitating side effects. Targeted drug delivery stands as an alternative to chemotherapy, with the potential to improve upon its low efficacy and systemic toxicity. Among...

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Detalles Bibliográficos
Autores principales: Akkapeddi, Padma, Azizi, Saara-Anne, Freedy, Allyson M., Cal, Pedro M. S. D., Gois, Pedro M. P., Bernardes, Gonçalo J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005007/
https://www.ncbi.nlm.nih.gov/pubmed/29997785
http://dx.doi.org/10.1039/c6sc00170j