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Differential antiviral activities of respiratory syncytial virus (RSV) inhibitors in human airway epithelium

OBJECTIVES: We report the use of reconstituted 3D human airway epithelium cells (HuAECs) of bronchial origin in an air–liquid interface to study respiratory syncytial virus (RSV) infection and to assess the efficacy of RSV inhibitors in (pre-)clinical development. METHODS: HuAECs were infected with...

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Detalles Bibliográficos
Autores principales: Mirabelli, Carmen, Jaspers, Martine, Boon, Mieke, Jorissen, Mark, Koukni, Mohamed, Bardiot, Dorothée, Chaltin, Patrick, Marchand, Arnaud, Neyts, Johan, Jochmans, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005027/
https://www.ncbi.nlm.nih.gov/pubmed/29596680
http://dx.doi.org/10.1093/jac/dky089