Inositol trisphosphate receptor-mediated Ca(2+) signalling stimulates mitochondrial function and gene expression in core myopathy patients

Core myopathies are a group of childhood muscle disorders caused by mutations of the ryanodine receptor (RyR1), the Ca(2+) release channel of the sarcoplasmic reticulum. These mutations have previously been associated with elevated inositol trisphosphate receptor (IP3R) levels in skeletal muscle myo...

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Detalles Bibliográficos
Autores principales: Suman, Matteo, Sharpe, Jenny A, Bentham, Robert B, Kotiadis, Vassilios N, Menegollo, Michela, Pignataro, Viviana, Molgó, Jordi, Muntoni, Francesco, Duchen, Michael R, Pegoraro, Elena, Szabadkai, Gyorgy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005141/
https://www.ncbi.nlm.nih.gov/pubmed/29701772
http://dx.doi.org/10.1093/hmg/ddy149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005141/
https://www.ncbi.nlm.nih.gov/pubmed/29701772
http://dx.doi.org/10.1093/hmg/ddy149

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