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Identification of DEAD-Box RNA Helicase DDX41 as a Trafficking Protein That Involves in Multiple Innate Immune Signaling Pathways in a Zebrafish Model

DDX41 is an important sensor for host recognition of DNA viruses and initiation of nuclear factor-κB (NF-κB) and IFN signaling pathways in mammals. However, its occurrence and functions in other vertebrates remain poorly defined. Here, a DDX41 ortholog [Danio rerio DDX41 (DrDDX41)] with various cons...

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Detalles Bibliográficos
Autores principales: Ma, Jun-xia, Li, Jiang-yuan, Fan, Dong-dong, Feng, Wei, Lin, Ai-fu, Xiang, Li-xin, Shao, Jian-zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005158/
https://www.ncbi.nlm.nih.gov/pubmed/29942316
http://dx.doi.org/10.3389/fimmu.2018.01327