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PU.1 Is Required for the Developmental Progression of Multipotent Progenitors to Common Lymphoid Progenitors

The transcription factor PU.1 is required for the development of mature myeloid and lymphoid cells. Due to this essential role and the importance of PU.1 in regulating several signature markers of lymphoid progenitors, its precise function in early lymphopoiesis has been difficult to define. Here, w...

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Detalles Bibliográficos
Autores principales: Pang, Swee Heng Milon, de Graaf, Carolyn A., Hilton, Douglas J., Huntington, Nicholas D., Carotta, Sebastian, Wu, Li, Nutt, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005176/
https://www.ncbi.nlm.nih.gov/pubmed/29942304
http://dx.doi.org/10.3389/fimmu.2018.01264