Rational design of supramolecular hemin/G-quadruplex–dopamine aptamer nucleoapzyme systems with superior catalytic performance

The rational design of a set of hemin/G-quadruplex (hGQ)–dopamine binding aptamer (DBA) conjugates, acting as nucleoapzymes, is described. The nucleoapzyme constructs consist of a hGQ DNAzyme as a catalytic unit and DBA as a substrate binding unit that are brought into spatial proximity by a duplex...

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Detalles Bibliográficos
Autores principales: Albada, H. Bauke, Golub, Eyal, Willner, Itamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005209/
https://www.ncbi.nlm.nih.gov/pubmed/29997801
http://dx.doi.org/10.1039/c5sc04832j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005209/
https://www.ncbi.nlm.nih.gov/pubmed/29997801
http://dx.doi.org/10.1039/c5sc04832j

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