When the inhibitor tells more than the substrate: the cyanide-bound state of a carbon monoxide dehydrogenase

Carbon monoxide dehydrogenase (CODH) is a key enzyme for reversible CO interconversion. To elucidate structural and mechanistic details of CO binding at the CODH active site (C-cluster), cyanide is frequently used as an iso-electronic substitute and inhibitor. However, previous studies revealed conf...

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Detalles Bibliográficos
Autores principales: Ciaccafava, Alexandre, Tombolelli, Daria, Domnik, Lilith, Fesseler, Jochen, Jeoung, Jae-Hun, Dobbek, Holger, Mroginski, Maria Andrea, Zebger, Ingo, Hildebrandt, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005268/
https://www.ncbi.nlm.nih.gov/pubmed/29997808
http://dx.doi.org/10.1039/c5sc04554a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005268/
https://www.ncbi.nlm.nih.gov/pubmed/29997808
http://dx.doi.org/10.1039/c5sc04554a

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